Kusagwirizana kumabwera m'maganizo zikafika pa Total IgE (Total Immunoglobulin E). Chifukwa m'zaka za m'mbuyomu, zinkadziwika kuti chiwerengero cha IgE chinawonjezeka kokha m'matenda osagwirizana.
Masiku ano, chitukuko cha matekinoloje azachipatala ndi kugawana zochitika ndi maphunziro a sayansi zasonyeza kuti chiwerengero cha IgE m'magazi athu chimakwera chifukwa cha zinthu zambiri, kuphatikizapo matenda ena, matenda a autoimmune ndi kutupa, kupatulapo matenda opatsirana.
Kodi Total IgE Test ndi chiyani?
Kwa anthu ena, chitetezo cha mthupi chimapanga ma antibodies ku chinthu chilichonse, ngakhale sichimayambitsa matenda. Tiyeni tifotokoze ndi chitsanzo; Udzu kwenikweni siwovulaza thanzi la munthu. Komabe chitetezo cha m’thupi cha anthu ena chimaona kuti udzu ndi wovulaza ndipo umatulutsa ma IgE olimbana ndi mdani ameneyu.
Thupi limapanga ma IgE apadera pa chinthu chilichonse chomwe amachilandira ngati allergen. Mwachitsanzo, mungu-igE yeniyeni imapangidwa m'mwazi wa munthu yemwe ali ndi vuto la mungu, pomwe fumbi-indu yeniyeni ya IgE imapangidwa mwa munthu yemwe ali ndi vuto la fumbi. Kuchuluka kwa ma IgE onsewa m'thupi la munthu kumatha kutchedwa IgE yonse.
Timatcha mayeso a biochemical, momwe mamolekyu onse a IgE m'magazi athu amayezedwa, Total IgE Test.
Kodi Mayeso Onse a IgE Achitidwa Chiyani? Chifukwa Chiyani Total IgE Ikukwera?
• Zina mwa matenda okhudzana ndi kulephera kwa chitetezo cha mthupi, makamaka matenda opatsirana, mitundu ina ya matenda, zotupa zosiyanasiyana, matenda otupa kapena autoimmune amatha kuwonjezera mlingo wa Total IgE m'magazi athu.
Kuyesa kwa labotale komwe kumayesedwa pakuwunika matenda okhudzana ndi kuchuluka kwa IgE ndikokwanira kuyesa kwa IgE.
• Mulingo wa IgE wonse woposa 1000 kU/L umathandizira kuzindikira kwa bronchopulmonary aspergillosis ngati pali zopezeka zachipatala pamodzi nazo. Matendawa amadziwika kuti ABPA mwachidule. ABPA imawoneka mwa odwala omwe ali ndi cystic fibrosis kapena mphumu. Choyambitsa chomwe chimapangitsa ABPA kukula ndi bowa Aspergillus.
• Kuonjezera apo, mayeso onse a IgE ndi mayeso othandizira kuti awone ngati wodwala yemwe wapezeka ndi matenda osagwirizana nawo ali woyenera kuthandizidwa ndi anti-IgE komanso kukonzekera mlingo wa chithandizo.
Zaka zam'mbuyomo, kuyesa kwa Total IgE kunkagwiritsidwa ntchito poyesa ngati munthu ali ndi ziwengo. Komabe, zidziwitso zatsopano zamankhwala zomwe zapezedwa lero zawonetsa kuti mulingo wa IgE wokwanira sungagwiritsidwe ntchito pawokha pozindikira kuti ali ndi vuto la ziwengo, komanso kuti IgE yonse imakwera m'mikhalidwe yosiyana kusiyapo ziwengo.
Kuphatikiza apo, ndi njira zodziwira matenda zomwe zapangidwa masiku ano, ma antibodies enieni a IgE okhudzana ndi 100s azinthu zomwe zingakhale zosagwirizana nazo zimatha kuyezedwa mu dontho limodzi la magazi nthawi imodzi ndi njira zoyezera ma cell.
Mafunso Ofunsidwa Kawirikawiri
Ngati IgE yonse ili yokwera, kodi zikutanthauza kuti ndili ndi ziwengo?
Zakudya zina, nthata, tinthu tating'onoting'ono tomwe timadya tinthu ting'onoting'ono tomwe timatuluka m'thupi la munthu m'malo monga makapeti ndi mabedi, nyama zina, mamolekyu omwe timakumana nawo kudzera m'kupuma, ndipo zinthu zina zamankhwala zimatha kukhala zosokoneza thupi lathu. Anthu omwe ali ndi ziwengo amapanga-ma antibodies enieni a IgE pa chilichonse mwazinthu izi. Titha kunena kuti Total IgE ndiye kuchuluka kwa ma IgE onsewa.
Komabe, mlingo wa IgE m’mwazi sukwera kokha pamene pali ziwengo. Matendawa sangadziwike poyesa mulingo wa IgE wokha.
Chifukwa chakuti mlingo waukulu wa IgE wokwanira m’mwazi wathu ungayesedwenso m’matenda ena opatsirana, makamaka majeremusi, mitundu ina ya khansa ndi matenda a autoimmune, kusiyapo matenda osagwirizana nawo.
Kuphatikiza apo, mwa odwala ena omwe sali osagwirizana nawo, mulingo wa IgE ukhoza kuyeza pamilingo yotsika kapena yabwinobwino. Mitundu iyi ya ziwengo si-IgE-mediated non-IgE allergies. Matenda a m'mimba angaperekedwe ngati chitsanzo cha mtundu uwu wa ziwengo. M'matumbo a m'mimba, matendawa amatha kupangidwa potsatira zizindikiro zachipatala za wodwalayo.
Nkhaniyi siyenera kuganiziridwa ngati malangizo achipatala. Chonde lankhulani ndi dokotala musanasinthe chilichonse pazaumoyo wanu.