Choyamba, tiyenera kudziwa kuti tsitsi ndi mbali ya thupi ndipo lili ndi zambiri zokhudza kagayidwe kachakudya m’thupi. Thupi likamamwa mankhwala, zigawo za mankhwalawa zimazungulira m'magazi kuti zifike ku tsitsi. Pakukula kwa tsitsi, ma metabolites awa amayikidwa pang'onopang'ono mkati mwa tsitsi, kupanga mawonekedwe anthawi yake.

Kuyeza mankhwalazachokera pa mfundo imeneyi. Pogwiritsa ntchito njira zowunikira zapamwamba, asayansi amatha kuchotsa mankhwala kuchokera kutsitsi la munthu, kuphatikiza ma metabolites amankhwala osiyanasiyana.

Ubwino umodzi waukadaulo uwu ndikuti posanthula chitsanzo cha tsitsi la munthu kapena thupi lake, titha kumvetsetsa kugwiritsa ntchito mankhwala m'miyezi isanu ndi umodzi yapitayo. Kuyezetsa tsitsi kungapereke chidziwitso kwa nthawi yayitali kusiyana ndi kuyezetsa mkodzo kapena magazi, zomwe ndizofunikira pakuwunika kwanthawi yayitali kwa kugwiritsa ntchito mankhwala osokoneza bongo. Komanso, kuzindikira tsitsi kumatha kuyang'ana mitundu yosiyanasiyana ya mankhwala, kuchepetsa njira yovuta yowunika mankhwala;