MOP / MET / MOP cov plaub hau tshuaj taug qab ceev cov khoom siv
Taw qhia
MET, feem ntau hu ua "crystal", rau cov dawb huv siv lead ua.Nws cov mis molecular yog C10H15N, thiab nws cov qauv qauv yog
.Tom qab noj yuav ua rau lub hauv paus paj hlwb excitement, txawv txav euphoria, rhiab heev rhiab heev, thiab consciously nquag, lub plawv dhia thiab ua tsis taus pa sai, ntev-lub sij hawm los yog ib tug loj tus naj npawb ntawm yooj yim rau tsim kam rau ua thiab dependence.
Morphine belongs rau opioid alkaloid thiab yog ib feem tseem ceeb ntawm cov tshuaj opioid. Nws cov mis molecular yog C17H19NO3 thiab nws cov qauv qauv yog. Morphine yog ib tug ntshiab opioid receptor agonist nrog muaj zog analgesic nyhuv. Yog li ntawd, nws yog siv raws li ib tug narcotic analgesic nyob rau hauv cov tshuaj. Kev siv ntau dhau ntawm morphine tuaj yeem ua rau mob lom thiab yooj yim ua rau kev zam thiab kev quav tshuaj.
Kev tshuaj xyuas plaub hau tau dhau los ua ib qho kev xaiv thiab ntxiv rau kev tshawb nrhiav kev siv tshuaj yeeb. Feem ntau, cov tshuaj hauv cov zis, ntshav thiab qaub ncaug yog metabolized huv si tom qab 7 hnub ntawm kev haus luam yeeb. Piv nrog rau kev tshuaj xyuas cov kua hauv lub cev, cov plaub hau muaj qhov zoo dua.Ntawm qhov kev tshawb nrhiav qhov rai (los ntawm 1 lub lis piam mus rau ob peb lub hlis); Cov plaub hau tsom xam muab cov duab sib txuas ntawm qhov ntev - lub sij hawm raug.
Npaj siv
Ib qho kev sim sai rau kev kuaj pom cov tshuaj hauv tib neeg cov plaub hau.
Kev tshuaj xyuas plaub hau tau dhau los ua ib qho kev xaiv thiab ntxiv rau kev tshawb nrhiav kev siv tshuaj yeeb. Feem ntau, cov tshuaj hauv cov zis, ntshav thiab qaub ncaug yog metabolized huv si tom qab 7 hnub ntawm kev haus luam yeeb. Piv nrog rau kev tshuaj xyuas cov kua hauv lub cev, cov plaub hau muaj qhov zoo dua.Ntawm qhov kev tshawb nrhiav qhov rai (los ntawm 1 lub lis piam mus rau ob peb lub hlis); Cov plaub hau tsom xam muab cov duab sib txuas ntawm qhov ntev - lub sij hawm raug.
Cov tshuaj yog metabolized nyob rau hauv qhov kev txiav txim ntawm cov ntshav lipid enzyme tom qab nkag mus rau tib neeg lub cev, thiab ntxiv metabolized tom qab nkag mus rau lub siab. Muaj ntau cov tshuaj thiab cov metabolites nkag mus rau hauv cov plaub hau, uas feem ntau yog ua ke nrog melanin thiab lwm yam tshuaj nyob rau hauv lub pulp kab noj hniav ntawm cov plaub hau.
Cov plaub hau kev loj hlob yog li ntawm 1 cm ib hlis twg, thiab cov tshuaj ua ke nrog cov plaub hau yuav loj hlob rau pem hauv ntej nrog cov plaub hau es tsis txhob kis raws cov plaub hau ncej. Cov plaub hau yog cim raws li cov hauv paus hniav, xaus thiab txiav mus rau hauv ob peb ntu, thiab txhua seem raug ntsuas cais. Raws li kev ntsuas ntawm qhov tshwm sim thiab qhov kev loj hlob ntawm cov plaub hau, lub sij hawm ntawm kev nqus tshuaj thiab tus nqi ntawm kev siv yeeb tshuaj tuaj yeem kwv yees kwv yees kwv yees. Qhov no yog cov ntshav, tso zis toxicity tsom xam uas tam sim no tsis tuaj yeem ua, thiab qhov ntawd yog ib qho ntawm cov laj thawj rau kev nyiam ntawm cov neeg ua haujlwm tshuaj toxicological.
Kev siv cov khoom no yuav tsum ua kom haum nrog Immunofluorescence quantitative analyzer tsim los ntawm Hangzhou Laihe Biotech Co., Ltd. (Model: FA - LF100C).
Nta
1 Cov khoom no siv lub hauv paus ntsiab lus ntawm immunochromatography kom ceev nrooj KET cov ntsiab lus.
2 Siv high-purity raw cov ntaub ntawv thiab high- zoo cov ntaub ntawv, nws qhia tau hais tias tsis tshua muaj siab rhiab heev thiab tshwj xeeb.
3. Yooj yim rau kev khiav lag luam
Kev ua haujlwm
1. Kev npaj: tig rau cov plaub hau tshuaj xyuas kab mob ntawm Hangzhou Laihe Biotech Co., Ltd.
2. Ua ntej kuaj, rov kho cov khoom kuaj, cov plaub hau lysate tsis thiab daim npav ID rau hauv chav sov (15-30 C). Qhia qhib lawv tom qab rov qab mus rau chav tsev kub (15 - 30 ° C)
3.Nyeem daim npav ID: paub meej tias daim npav ID puas haum nrog batch naj npawb ntawm cov khoom kuaj, ntxig daim npav ID, thiab nyem rau ntawm lub pob ntawv lees paub ntawm lub ntsuas ntsuas lub vijtsam nyeem daim npav ID, tom qab ntawd cov khoom siv tuaj yeem kuaj pom. .
4. Xaiv "cov plaub hau" hauv cov qauv qauv ntawm lub ntsuas ntsuas qhov screen.
5. Txiav 5mg plaub hau (txog 10 * 10cm ntev plaub hau) uas yuav tsum tau kuaj rau hauv 1-2mm seem nrog txiab, sau los ntawm ib daim ntawv hnyav, ces co nws mus rau hauv lub centrifuge raj uas muaj cov plaub hau lysate buffer, npog lub centrifuge raj cap. , co thiab sib tov rau 1 feeb. Siv lub dropper los nqus cov supernatant ntawm cov plaub hau lysate tsis thiab ntxiv ob tee rau hauv cov qauv qhov ntawm cov khoom kuaj lub phaj.
6. Kev nyeem ntawv: cov khoom siv kuaj lub sijhawm ua haujlwm yog li 3 feeb tom qab ntxiv cov qauv, thiab tom qab ntawd ntxig cov khoom siv ntsuas rau hauv lub ntsuas tam sim tom qab qhov tshuaj tiv thaiv tas. Nyem qhov "test" khawm. Lub kaw lus yuav cia li nyeem cov khoom siv Test thiab muab cov qhab nia xeem. Tom qab 5 feeb, qhov kev xeem tsis raug.
Kev txhais cov ntsiab lus
Thaum kuaj pom qhov tshwm sim ntawm MET (T1) < 0.1ng / mg, nws raug txiav txim tsis zoo.
Thaum kuaj pom qhov tshwm sim ntawm MET (T1) ≥ 0.1ng / mg, nws raug txiav txim kom zoo.
Thaum kuaj pom qhov tshwm sim ntawm MOP (T2) < 0.1ng / mg, nws raug txiav txim tsis zoo..
Thaum kuaj pom qhov tshwm sim ntawm MOP (T2) ≥ 0.1ng / mg, nws raug txiav txim kom zoo.
Kev ceev ntiag tug